6 research outputs found

    Legemidler mot kols

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    Reaction of sandeel to seismic shooting: a field experiment and fishery statistics study

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    The reaction to seismics of lesser sandeel (Ammodytes marinus) was investigated in the North Sea using steel cages to enclose the fish while burried in the sand. Three cages were exposed to seismic shooting from SV "Falcon Explorer" during two days in May 2002. The sandeel behaviour was recorded on video from an ROV, and data analysed. The sandeel seemed to react slightly, but did not flee to the bottom. No injury or mortality caused by seismic shooting was observed. The fishing vessels tended to avoid the seismic area, and the days after the shooting the landings of sandeel declined temporarily. NORSK SAMMENDRAG: Atferden hos tobis (Ammodytes marinus) ble undersÞkt ved Ä stenge fisken inne i stÄlbur og overvÄke den under seismisk skyting fra et seismikkfartÞy i NordsjÞen. Til dette ble det anvendt en ROV pÄmontert videokameraer, og opptakene ble senere analysert. Det ble pÄvist atferd som kan tolkes som fluktreaksjoner, men tobisen svÞmte ikke mot bunnen for Ä grave seg ned. Det ble heller ikke pÄvist skade eller dÞd som skyldtes seismikk. Under eksperimentet syntes fiskeflÄten i noen grad Ä sÞke vekk fra omrÄdet og de leverte fangstene sank midlertidig et par dager

    COPD - do the right thing

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    A gap exists between guidelines and real-world clinical practice for the management and treatment of chronic obstructive pulmonary disease (COPD). Although this has narrowed in the last decade, there is room for improvement in detection rates, treatment choices and disease monitoring. In practical terms, primary care practitioners need to become aware of the huge impact of COPD on patients, have non-judgemental views of smoking and of COPD as a chronic disease, use a holistic consultation approach and actively motivate patients to adhere to treatment. This article is based on discussions at a virtual meeting of leading Nordic experts in COPD (the authors) who were developing an educational programme for COPD primary care in the Nordic region. The article aims to describe the diagnosis and lifelong management cycle of COPD, with a strong focus on providing a hands-on, practical approach for medical professionals to optimise patient outcomes in COPD primary care

    The burden of mild asthma: Clinical burden and healthcare resource utilisation in the NOVELTY study

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    Background: Patients with mild asthma represent a substantial proportion of the population with asthma, yet there are limited data on their true burden of disease. We aimed to describe the clinical and healthcare resource utilisation (HCRU) burden of physician-assessed mild asthma.Methods: Patients with mild asthma were included from the NOVEL observational longiTudinal studY (NOVELTY; NCT02760329), a global, 3-year, real-world prospective study of patients with asthma and/or chronic obstructive pulmonary disease from community practice (specialised and primary care). Diagnosis and severity were based on physician discretion. Clinical burden included physician-reported exacerbations and patient-reported measures. HCRU included inpatient and outpatient visits.Results: Overall, 2004 patients with mild asthma were included; 22.8% experienced ≄1 exacerbation in the previous 12 months, of whom 72.3% experienced ≄1 severe exacerbation. Of 625 exacerbations reported, 48.0% lasted >1 week, 27.7% were preceded by symptomatic worsening lasting >3 days, and 50.1% required oral corticosteroid treatment. Health status was moderately impacted (St George's Respiratory Questionnaire score: 23.5 [standard deviation ± 17.9]). At baseline, 29.7% of patients had asthma symptoms that were not well controlled or very poorly controlled (Asthma Control Test score <20), increasing to 55.6% for those with ≄2 exacerbations in the previous year. In terms of HCRU, at least one unscheduled ambulatory visit for exacerbations was required by 9.5% of patients, including 9.2% requiring ≄1 emergency department visit and 1.1% requiring ≄1 hospital admission.Conclusions: In this global sample representing community practice, a significant proportion of patients with physician-assessed mild asthma had considerable clinical burden and HCRU

    Treatable traits in the NOVELTY study

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    CorrigendumVolume 27, Issue 12, Respirology, pages: 1095-1095. First Published online: November 6, 2022 10.1111/resp.14406International audienceAsthma and chronic obstructive pulmonary disease (COPD) are two prevalent and complex diseases that require personalized management. Although a strategy based on treatable traits (TTs) has been proposed, the prevalence and relationship of TTs to the diagnostic label and disease severity established by the attending physician in a real-world setting are unknown. We assessed how the presence/absence of specific TTs relate to the diagnosis and severity of 'asthma', 'COPD' or 'asthma + COPD'
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